GeneTack: tools for frameshift prediction

Clusters corresponding to Known Cases of Programmed Frameshifting

  1. Release Factor 2, +1
  2. DNA polymerase III, -1
  3. HTH_Tnp_1 (Transposase), -1
  4. HTH_Tnp_1 (Transposase), +1
  5. HTH_Tnp_IS630 (Transposase), -1
  6. HTH_Tnp_IS630 (Transposase), +1
  7. DDE_Tnp_1 (Transposase), -1
  8. DDE_Tnp_1 (Transposase), +1
  9. DDE_Tnp_1 (Transposase), +1
  10. DDE_Tnp_IS1 (Transposase), -1
  11. DDE superfamily endonuclease, -1

New Experimentally Verified Programmed Frameshifts

           
  1. Magnesium chelatase (FS efficiency: 60%, 41%, 17%)
  2. DUF111 (FS efficiency: 39%, 34%)
  3. DUF772 (FS efficiency: 24%, 9%)
  4. Spore germination protein (FS efficiency: 13%, 4%)
  5. ATP-gua_Ptrans | UVR (FS efficiency: 8%)
  6. Phage tail assembly chaperone (FS efficiency: 7%, 6%)
  7. Tetraacyldisaccharide kinase, acyltransferase (FS efficiency: 7%)
  8. Cyclic-nucleotide phosphodiesterase (FS efficiency: 6%)
  9. phaP protein / Dehydratase (maoC family) (FS efficiency: 6%)
  10. Bac_DNA_binding | Formyl_trans_N (FS efficiency: 6%, 3%)

Experimentally Verified Cases of Internal Initiation (Translational Coupling)

           
  1. ABC transporter
  2. Aminotran_1_2 | Dala_lig_C | Dala_Dala_lig_N | GntR
  3. DMRL_synthase | NusB
  4. Ribosomal RNA methyltransferase
  5. Preprotein translocase subunit SecA
  6. Thymidylate kinase
  7. Fumarylacetoacetase / Homogentisate 1,2-dioxygenase
  8. MATE efflux family protein (transporter)
  9. Epimerase | URO-D
  10. DNA glycosylase / Dephospho-CoA kinase

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